The Michael Addition + 1,4 Additions with Soft Nucleophiles
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https://joechem.io/videos/43 for video on jOeCHEM and attached worksheet + solution (below video on jOeCHEM aka the link). https://joechem.io/videos/43 for video on jOeCHEM and attached worksheet + solution (below video on jOeCHEM aka the link). In this video, we look at a functional group called enones--or alpha, beta unsaturated ketones--and how they are prime candidates to be attacked by nucleophiles in a 1,4 fashion, as opposed to the 1,2 way we're used to. We will specifically look at the Michael Addition, which is when an enolate nucleophile attacks an enone. However, you can attack enones in a 1,4 fashion with any \"soft\" nucleophile, and we'll see an example of that by attacking an enone with a cuprate nucleophile.