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EAS Reactions with Phenol

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https://joechem.io/videos/161 for video on jOeCHEM and attached worksheet + solution (below video on jOeCHEM aka the link). https://joechem.io/videos/161 for video on jOeCHEM and attached worksheet + solution (below video on jOeCHEM aka the link). In this video, we'll lean on our previous benzene chemistry knowledge as we look at EAS rxns with phenol. Since the -OH group is a strong EDG, phenol directs additional groups in an ortho/para fashion. However, there is one thing to watch out for when doing Friedel-Crafts Acylations--check the video to find out what.

Tags: mechanisms, benzene-substituents, free

All Videos:

10. EAS Reactions with Phenol

1. Review of the Benzylic Position--SN1, SN2, Acid Base, and Radical Addition

2. Oxidation at the Benzylic Position--KMnO4 and MnO2

3. Reduction/Ether Cleavage via Hydrogenation

4. Introduction to Phenols, Characteristics and Naming

5. Nucleophilic Aromatic Ipso Substitution (NAS)

6. Nucleophilic Aromatic Ipso Substitution Examples Galore

7. NAS with Haloarenes, Various Pathways

8. Making Phenols Using Diazotization & Arenediazonium Ions

9. Chemistry of Phenols--They\'re Alcohols Too!

11. The Hydroxymethylation of Phenol

12. The Kolbe Reaction

13. Claisen Rearrangements Explained

14. Cope and Oxy-Cope Rearrangements Explained

EAS Reactions with Phenol - jOeCHEM